Study: Specific Sleeping Pill Blocks Tau-Mediated Neurodegeneration in Mice
New research suggests the orexin receptor antagonist prevents harmful protein buildup in the brain.
Tag: Mice
All
Latest
All
Latest
Known Drug Can Restore Brain’s Waste-Clearing Ability in Aging Mice
Researchers have used a hormone-like compound to restore the brain’s ability to clear toxic...
All
Latest
Restless Legs Syndrome Research Will Become Easier to Compare & Replicate
The International Restless Legs Syndrome Study Group published consensus guidelines on rodent models of RLS.
Pulling an All-Nighter Has an Antidepressant Effect That Lasts for Days
A single night of sleep deprivation can trigger a rapid and temporary antidepressant effect, according to Northwestern University neurobiologists.
Read More
Centessa’s Investigational ORX750 for Narcolepsy Undergoing IND-Enabling Activities
Centessa Pharmaceuticals is focused on moving ORX750 through IND-enabling studies, obtaining IND clearance, and initiating clinical development of ORX750, which has shown potential to treat narcolepsy in preclinical studies.
Read More
Why Shift Work Has You Reaching for That Extra Snack
Scientists have uncovered why night shift work is associated with changes in appetite.
Read More
A Surprising Way to Disrupt the Sleep/Wake Cycle
Researchers identified a structure in the circadian mRNA Period2 that affects the sleep/wake cycle, particularly during the early morning and late evening.
Read More
Surprisingly, Mice that Drink Caffeine Sleep More Solidly
Chronic caffeine consumption in mice not only leads to more solid sleep but also increases brain blood flow during sleep—which could offer neuroprotective benefits, a new study finds.
Read More
Nesting in Mice Unveils the Brain’s Innate Drive for Pre-Sleep Prep
The specific brain wiring responsible for initiating nesting behaviors before sleep in mice has been identified by researchers, suggesting that proper sleep preparation is likely a hard-wired survival trait.
Read More
Experimental Insomnia Drug Prevents Oxycodone Relapse
New findings suggest that treating insomnia can stop opioid-seeking behavior, even after ending treatment.
Read More
Bright Light’s Role in Alleviating Stress-Induced Sleep Disturbances
Researchers have identified the neural pathway behind the link between chronic stress and sleep disturbance and, at the same time, explain how bright-light treatment is able to counter it.
Read More
Molecular Pathway that Controls Sleep Rhythm ID’d
Researchers from Japan have found new details about the molecular processes that govern sleep/wake rhythms in mice.
Read More
Mice Study Clues Researchers in to How Deep Sleep Is Regulated by the Brain
If replicated in further animal models, investigators say the findings could lay the groundwork for designing therapies that precision-target a specific protein to induce deep sleep.
Read More
Memories ‘Lost’ After Sleep Deprivation Brought Back in Mice
Findings from the study open up avenues to test whether a drug already clinically approved for use in humans can be applied to restore access to “lost” memories in humans.
Read More
What’s Sex Got to Do with Narcolepsy?
New mouse studies suggest potential sex and gender differences in narcolepsy symptoms, but will the dissimilarities extend to humans?
Read More
Noradrenaline Wakes Up Mice 100+ Times a Night—And Is Linked to ‘Super’ Memory
A new study from the University of Copenhagen found that the refreshing part of sleep is driven by waves of transmitter noradrenaline.
Read More
Breathing Coordinates Neuronal Activity Throughout Brain (Mice Study)
Respiration entrains and coordinates neuronal activity in all investigated brain regions by modulating the excitability of these circuits.
Read More
Restoring Normal Sleep Reduces Amyloid-Beta Accumulation in Mouse Model of Alzheimer’s Disease
The study suggests that the thalamic reticular nucleus not only may play a previously unsuspected driving role in symptoms associated with Alzheimer’s, but also that restoring its normal activity could be a potential therapeutic approach
Read More