Category: Breathing Disorders

Breathing Disorders

Incannex Meets with FDA in Pre-IND Meeting for Sleep Apnea Drug Candidate

Incannex characterized the pre-investigational new drug application (pre-IND) meeting about IHL-42X as “highly constructive.”

Breathing Disorders

Axsome Completes US Acquisition of Sunosi

'The Sunosi acquisition marks the transformation of Axsome into a commercial neuroscience company and reflects our commitment to the millions of people living with serious neurologic and psychiatric conditions.'

Breathing Disorders

Inspire Trialed in Children with Down Syndrome and Sleep Apnea

Children with Down syndrome and sleep apnea are more likely to experience aggressive behavior, brain fogging, and a loss of nearly 10 points in IQ compared to those without.

Obstructive Sleep Apnea

Sulthiame Lowers AHI At Least 50% in Trial

Sulthiame, a carbonic anhydrase inhibitor, lowered obstructive sleep apnea by more than 20 events/hour, a notable decline for a drug trial.

Central Sleep Apnea

Years In, Neurostimulation for Sleep Apnea Keeps AHI Down

Neurostimulators don't have decades of patient data like CPAP, but Inspire and remedē's 1- and 5-year outcome studies show sustained benefits.

Hypoventilation

CPAP vs NIV for Ambulatory Patients With Obesity Hypoventilation Syndrome

Continuous positive airway pressure (CPAP) may be a preferred alternative to noninvasive ventilation (NIV) as first-line therapy in stable ambulatory patients with obesity hypoventilation syndrome (OHS) and concurrent...

Hypoxia

In Rats, Inducing Low Oxygen During Sleep Causes Autism-Like Changes in Male Offspring

Affected offspring had excessive activity of the mTOR pathway, a feature identified in the cortex of humans with autism.

Snoring

Will Oral Appliances One Day Be an Early Intervention for Alzheimer’s Disease?

A study examines whether alleviating snoring in people with mild cognitive impairment and with Alzheimer’s influences their cognition.