Vanda Preps sNDA for HETLIOZ in Insomnia
Vanda’s trial results of HETLIOZ (tasimelteon) for insomnia suggest that circadian misalignment may be the etiology behind chronic primary insomnia for many patients.
Vanda’s trial results of HETLIOZ (tasimelteon) for insomnia suggest that circadian misalignment may be the etiology behind chronic primary insomnia for many patients.
Previous studies completed by the UB researchers found that the NSAIDs ibuprofen and ketoprofen also affected the movement of GHB in the body.
"These analyses further characterize the efficacy and safety profile of WAKIX and its broad clinical utility for the treatment of excessive daytime sleepiness or cataplexy in adult patients with narcolepsy."
Thirteen abstracts sponsored by Jazz Pharmaceuticals and five abstracts from investigator-sponsored trials will be presented at SLEEP 2021.
Read MoreThere was no difference in sleep quality or duration between those who did and didn’t take these meds for 1 to 2 years, the findings show.
Read MoreSleep disorders are highly comorbid with a multitude of psychiatric disorders and narcolepsy can have a significant impact on a person’s daily functioning, which may greatly affect their social, emotional and psychological well-being, and quality of life.
Read MoreThe AAN presentation further quantifies the previously reported Phase 3 top-line results.
Read MoreMany commonly prescribed drugs—such as some sleep aids—are known to carry an increased risk of breaking a bone, by increasing falls, weakening bones, or both.
Read MoreReuters: The hikes could help make up for lost revenue as doctors visits and new prescriptions plummeted during the global lockdown.
Read MoreA literature review from Stanford University looks at how the popular narcolepsy medication sodium oxybate impacts heart health.
Read MoreResearchers studied the adverse events for 3,532 patients who had been prescribed Z-drugs and compared them to people with sleep disturbance who had not been prescribed sedatives and with patients who had been prescribed benzodiazepines.
Read MoreThe commission investigation has found that for several years, this “pay-for-delay” agreement eliminated Teva as a competitor and allowed Cephalon to continue charging high prices even if the main modafinil patent had long expired.
Read MoreSmith-Magenis Syndrome is a rare neurodevelopmental disorder, a defining feature of which is an “inverted” circadian rhythm.
Read MoreHealth Union, which creates condition-specific online patient communities, shared results from its Sleep Disorders In America survey.
Read MoreThe FDA says that Harmony Biosciences’ drug—previously approved for excessive daytime sleepiness in narcolepsy—works for cataplexy too. Harmony’s chief medical officer explains how this impacts healthcare practitioners and patients.
Read MoreResults of the double-blind, placebo-controlled, randomized-withdrawal, multicenter study were previously presented at World Sleep 2019.
Read MoreFDA approval of WAKIX for the treatment of cataplexy in adult patients with narcolepsy is based on two randomized, controlled trials.
Read MoreThough men and women can have different responses to medications—Ambien, for example, metabolizes more slowly in women, causing next-day grogginess—doctors may not know about these differences because most clinical trial data are biased toward men.
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