Category: Sleep & the Body

Sleep & the Body

Preclinical Research Highlights mGlu7 Modulation in Sleep Regulation

A newly published study shows that ADX71743, a selective mGlu7 inhibitor, significantly modulates sleep-wake regulation and stress-related neurochemistry in animal models.

Sleep & the Body

Lilly’s Investigational Triple Agonist Retatrutide Reduces OSA Severity in Phase 3 Trial

Phase 3 TRIUMPH-1 trial data show retatrutide reduced the AHI by up to 36.1 events per hour alongside substantial weight loss.

Sleep & the Body

Sleep as a Window Into Neurodegeneration

Watch a 1-hour webinar on the links between sleep and Alzheimer's disease and other neurodegenerative processes. It's available immediately on demand.

ADHD Brains Show Frequent Sleep-Like Activity During Wakefulness

Mar 20, 2026 | Brain, Impact During Wake

A new study reveals that brief bursts of sleep-like brain activity during wakefulness may explain attention lapses in adults with ADHD, opening doors for potential sleep-targeted treatments.

Wearable Data Links Sleep Disruption to IBD Inflammation

Mar 6, 2026 | Sleep & the Body

Researchers found that reduced REM sleep and increased light sleep signal active inflammation and upcoming flares in inflammatory bowel disease patients, even when symptoms are absent.

‘Measures of Sleep Are Decently Predictive of Preterm Birth’

Feb 27, 2026 | Reproduction

A study using actigraphy finds that sleep consistency offers better predictive power of preterm birth than average sleep duration.

What Should ‘Orthodontics’ Be Called, Anyway?

Feb 26, 2026 | Mouth & Upper Airway

And Why Does It Matter?

Study Links Sleep to Overnight Clearing of Alzheimer’s-Linked Proteins

Feb 24, 2026 | Brain

New research provides evidence that sleep-driven glymphatic activity moves amyloid beta and tau out of the brain and into the bloodstream.

Excessive Daytime Sleepiness May Raise Risk of Cognitive Problems After Surgery

Feb 5, 2026 | Brain

New research suggests preoperative sleepiness is a potential warning sign for perioperative neurocognitive disorders in older adults.

Afternoon Naps Facilitate Synaptic Reset and Enhance Learning Capacity

Feb 3, 2026 | Brain

Researchers found that short sleep periods reorganize nerve cell connections to clear space for new memories, a process previously thought to require a full night’s sleep.

Lofta, Accomplish Health to Collaborate on Medical Weight Loss for Sleep Apnea Patients

Jan 23, 2026 | Weight

The strategic alliance connects Lofta patients with virtual obesity care, including GLP-1 therapies and nutrition coaching, to address a key driver of disease severity.

Study Identifies SIRT6 as Key Regulator of Tryptophan Metabolism in Aging Brains

Jan 3, 2026 | Brain

New research finds the longevity protein’s absence shifts tryptophan pathways away from serotonin and melatonin production, impacting sleep and suggesting a new therapeutic target.

A Roadmap for Integrated Sleep-Obesity Care

Dec 16, 2025 | Weight

Mira Tadros, DO, spearheaded SOS—Mount Sinai’s Obesity & Sleep program—streamlining patient care.

Naväge Releases Nasal SaltPods Formulated for Daytime, Nighttime Use

Dec 12, 2025 | Mouth & Upper Airway, Over-the-Counter Treatments

The new premeasured capsules combine saline with essential oils for use with the company’s powered nasal irrigation system to relieve congestion and support better sleep.

Evidence of Bacterial Molecules in Mouse Brains Disrupts Long-Held Views of Sleep Regulation

Dec 8, 2025 | Brain

New findings serve to update a broader hypothesis that has been in development at WSU for years—proposing that sleep arises from communication between the body’s sleep regulatory systems and the multitude of microbes living inside us.

Sleep Is a Powerful Defense Against Alzheimer’s Disease

Nov 26, 2025 | Brain

Deep sleep activates the brain’s waste-clearing system, reducing harmful beta-amyloid and tau buildup. Maintain your sleep to help maintain brain health.

Sleep-Deprived Brains Trigger Cleansing Fluid Surges That Short-Circuit Attention

Nov 4, 2025 | Brain

MIT researchers find that cerebrospinal fluid waves, normally seen during sleep, intrude into wakefulness after sleep loss—briefly cleansing the brain but causing attention lapses.

Sleep Apnea May Amplify GLP-1 Survival Benefits in Type 2 Diabetes

Oct 23, 2025 | Diabetes, Prescription Drugs

A study of nearly 1.8 million adults with diabetes suggests patients with obstructive sleep apnea derive a 20% greater mortality reduction from GLP-1 therapy than those without the sleep disorder.