A psychologist explains what you need to know about the connection between Alzheimer’s and sleep in Psychology Today.
The role that amyloid plaque plays in Alzheimer’s disease is well-known, but here is a paradox that has confounded scientists for decades. You would think that Alzheimer’s patients would show large accumulations of amyloid plaque in the area of the brain responsible for long-term memory storage—the hippocampus. But that’s not true. In fact, Alzheimer’s patients show the greatest amount of amyloid accumulation in the mid-region of their frontal lobe. That is an area not particularly associated with memories, but it is associated with something else—sleep.