In a cohort of adults assessed for sleep issues, those in the highest quartile of apolipoprotein B to apolipoprotein A-I ratio were at the greatest risk for obstructive sleep apnea and insulin resistance, according to findings published in Nutrition, Metabolism & Cardiovascular Diseases.

“The ApoB/ApoA-I ratio is positively associated with the risk of prediabetes, diabetes, metabolic syndrome, nonalcoholic fatty liver disease and CVD,” Jian Guan MD, PhD, of the department of otorhinolaryngology-head and neck surgery at Shanghai Jiao Tong University Affiliated Sixth People’s Hospital in Shanghai, and colleagues wrote.

“Considering that [obstructive sleep apnea] may promote dyslipidemia, we hypothesized a positive association between severity of [obstructive sleep apnea] and the ApoB/ApoA-I.”