A study published in the European Journal of Endocrinology found that the risk of obstructive sleep apnea doubled in women with Cushing’s Syndrome.

The researchers found that women with Cushing’s syndrome were more likely to have obstructive sleep apnea and more symptomatic sleep apnea vs. controls (50% vs. 23%; P = .003), as well as higher mean AHI scores vs. controls (P = .005). Most patients in the cohort had mild sleep apnea (14 with Cushing’s syndrome; seven controls).

AHI was positively correlated with HOMA score (r = 0.281; P = .046) in patients with Cushing’s syndrome and controls, and serum cortisol was an independent predictor of AHI after controlling for BMI and HOMA scores, according to researchers.

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