Solriamfetol (Sunosi) significantly improved driving performance for patients with narcolepsy and daytime sleepiness due to obstructive sleep apnea, according to a pair of on-road driving studies sponsored by the drugmaker.

In the one-hour driving test, performed two hours after taking 300 mg solriamfetol or placebo, patients with narcolepsy showed less weaving with the active drug (difference in standard deviation of lateral positioning -1.9 cm, 95% CI -6.7 to 2.6, P=0.002), reported Frederick Vinckenbosch, MSc, of Maastricht University in the Netherlands.

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