Researchers at Massachusetts General Hospital say that urine tests might be able to detect sleep apnea in children with Down Syndrome.

Study participants provided urine samples collected before and after they completed hospital sleep studies called polysomnograms. Not only were there differences between the urinary biomarkers of participants with Down syndrome who did and did not have OSA – with a combination of four neurotransmitters most clearly distinguishing between the two groups – but there also were significant differences between the biomarker signatures of all participants with Down syndrome and those of the neurotypical control participants, regardless of the presence or absence of OSA.