New research funded by dental sleep appliance developer Panthera Dental will be presented at the American Academy of Dental Sleep Medicine (AADSM) and SLEEP 2024 annual meetings.

5-Year Real-World Study on Panthera Oral Appliances

Five-Year, Prospective, Multicenter, Real-world Study to Assess the long-term safety, Initial Management, and Effectiveness of a CAD/CAM, 3-D Printed Oral Appliance in the Treatment of Obstructive Sleep Apnea: Updated Interim Analysis (AADSM – Poster #14 (5/18 4-4:30) )

A 5-year Multi-Center Real-world Study Evaluating the Effectiveness and Use of CAD/CAM 3D-printed OAT to Treat OSA (SLEEP – Poster #252 (6/5, 10-11:45) and O-26 (6/5, 2:45-3:00) 

Panthera will share preliminary results from its real-world multicenter study, which is being conducted in France. The study mimics current standards of care for providing oral appliance therapy for obstructive sleep apnea patients. One of the most notable differences between France and the United States is the criteria for moderate or severe classifications, not mild. The study reports on participants in the first full year, from baseline to 12 months. The preliminary data support robust effectiveness and continued nightly use.

Finite Element Analysis

Finite Element Analysis (FEA) of a CAD/CAM, 3-D Printed Oral Appliance to Treat Obstructive Sleep Apnea (AADSM late-breaking abstract – Poster # 33 (5/18, 4-4:30))

Finite Element Analysis (FEA) Study to Assess Tooth Forces of a 3-D Printed Nylon Oral Appliance to Treat Obstructive Sleep Apnea (SLEEP late-breaking abstract – Poster #376 (6/4, 11-11:45)) 

Research and development are part of a medical device company’s commitment to demonstrate compliance with ISO 13485 to assess medical device safety and performance. This study was conducted to meet these requirements and provide a well-researched understanding of the stress/strain (forces) of the Panthera oral appliance therapy for sleep apnea using finite element analysis, a mathematical simulation model. 

Panthera commissioned a team of scientists with superior expertise to assess the biomechanical effects on teeth and periodontal ligaments. The abstract provides data to support the design and materials for the reduction of forces used in the manufacturing of the Panthera appliance.

Details Available at AADSM and SLEEP 2024

“Panthera always placed research and development at the forefront of the company,” says Marc Morisset, vice president of the Sleep Division at Panthera Dental, in a release. “These two ongoing research projects and our new research grant initiative confirm our dedication to continuously improving our patient-matched oral appliances, prioritizing comfort, compliance, and chair time efficiency.” 

The Panthera team will exhibit at the AADSM Annual Meeting (booth #320) and SLEEP 2024 (booth #1517).