Category: Pharmaceuticals

Pharmaceuticals

FDA Grants Fast Track Designation to Investigational Narcolepsy Treatment

The oral orexin 2 receptor agonist currently in phase 1b development for patients with narcolepsy.

Pharmaceuticals

Melatonin Can Be a Safe and Effective Sleep Aid for All Ages—But Product Inconsistencies and Improper Dosing Lead to Real Harms

Melatonin – a go-to sleep aid for kids and adults alike in many households in America – continues to create media buzz, with conflicting messages that leave people uncertain about its safety.

Pharmaceuticals

Drug Used Off-Label for Insomnia Improves Sleep But Impairs Next-Day Alertness in OSA Patients

Flinders University researchers have led a clinical trial examining how a commonly prescribed ‘sleeping pill’ affects sleep, breathing, and next‑day performance.

Prescription Drugs

Idorsia Reports Q1 2026 Results, Highlighting Pediatric Daridorexant Data and Expanding Clinical Evidence

The company’s first-quarter update emphasizes strong phase 2 results for daridorexant in children, ongoing real-world studies in patients with co-morbidities, and advancements in its sleep medicine pipeline.

Over-the-Counter Treatments

Saline Nasal Spray Shows Efficacy in Treating Pediatric Sleep-Disordered Breathing

A new Australian study finds that a simple saline nasal spray can resolve symptoms of obstructive sleep-disordered breathing in children, potentially reducing the need for surgery and specialist care.

Emerging Compounds

Alkermes to Present Sustained Efficacy Data for Alixorexton in Narcolepsy Type 1

Phase 2 Vibrance-1 study extension shows sustained improvements in patient-reported disease severity, cognitive functioning, and fatigue.