Patients with narcolepsy, especially narcolepsy type 1 (with cataplexy), have poorer nighttime sleep, according to a new research review.
The study authors included 65 case-control studies that compared narcolepsy patients with healthy controls (HCs) that reported differences in PSG-measured nighttime sleep parameters between the groups.
They also included 41 studies comparing patients of narcolepsy type 1(NT1) and type 2 (NT2), narcolepsy patients with and without rapid eye movement sleep behavior disorder (RBD)(n=4), and those positive or negative for human leukocyte antigen (HLA) DQB1*06:02 (n=3).
