A study demonstrates a higher risk of congenital anomalies and resuscitation at birth in newborns of mothers who have obstructive sleep apnea.
Preliminary results show that newborns of mothers with sleep apnea were more likely to be admitted to the intensive care unit (25.3% versus 8.1%) or special care nursery (34.9% versus 13.6%), and they were 2.76 times more likely to have resuscitation at birth and 2.25 times more likely to have a longer hospital stay. The risk for congenital anomalies also was 26% higher in babies of women with sleep apnea.
“Our results have shown that babies born to mothers with a diagnosis of obstructive sleep apnea are more likely to require resuscitative efforts at birth, be born preterm, and to require a stay in the neonatal intensive care unit compared to babies who were not exposed to maternal sleep apnea,” says principal investigator and lead author Ghada Bourjeily, MD, associate professor of medicine at Brown University and the Women’s Medicine Collaborative at The Miriam Hospital in Providence, RI, in a release.
Using data collected by the National Perinatal Information Center, the research team led by Bourjeily analyzed more than 1.4 million linked maternal and newborn records with a delivery hospitalization from 2010-2014. Less than 1% of the mothers had a diagnosis code of obstructive sleep apnea; however, mothers with sleep apnea had a higher likelihood of having obesity, pre-gestational hypertension, and diabetes.
“These findings add to our understanding of the extent of morbidities of maternal sleep apnea for the mother as well as the baby,” says Bourjeily. “The results further highlight the importance of identifying this condition in pregnancy and testing the impact of therapy on these complications.”
The research abstract was published recently in an online supplement of the journal Sleep (Abstract #0474) and presented Sunday, June 4, in Boston at SLEEP 2017.