The presence of sleep-disordered breathing among patients with acute coronary syndrome after primary PCI has been linked with increased incidence of major adverse cardiocerebrovascular events, according to Healio.
For this study, sleep-disordered breathing was defined as apnea-hypopnea index (AHI) five events per hour, apnea was defined as an interruption of airflow for 10 seconds and hypopnea was defined as a 50% increase in airflow related to 4% desaturation.
Overall, 126 patients had sleep-disordered breathing and 115 did not.
During a median follow-up of 5.6 years, the primary endpoint of major adverse cardiocerebrovascular events (MACCE), including all-cause death, ACS recurrence, nonfatal stroke and hospitalization for congestive HF, occurred in 21.4% of the group with sleep-disordered breathing vs. 7.8% of the group without sleep-disordered breathing (P = .006). The most common cause of MACCE in this cohort was hospitalization for congestive HF.