A study found the dopaminergic medication rotigotine and the ?-2-? ligands gabapentin enacarbil and pregabalin provide similar treatment effects for patients with restless leg syndrome, reports Neurology Advisor.
A total of 35 studies of patients with restless leg syndrome (n=7333) were included. Among these studies, gabapentin enacarbil as well as pregabalin and rotigotine demonstrated greater benefit than placebo (mean reduction in IRLS scores: -5.31 [-6.74 to -3.87], -5.20 [-6.91 to -3.49], and 5.17 [3.73 to 6.61], respectively).
