According to Medpage Today, an investigational nasal spray and exercise were shown to have an impact on the severity of adult nocturia in two studies.

In a phase III randomized clinical trial, a low-dose desmopressin nasal spray (SER120) reduced the number of voids per night in adults with nocturia, with a low risk of hyponatremia.

And a second study — a cross-sectional analysis of National Health and Nutrition Examination Surveys (NHANES) 2005-2010 data — found that exercise seemed to mitigate the excess risk of nocturia with inflammation as measured by level of C-reactive protein (CRP).

The results of both studies were presented during a press briefing at the 2016 meeting of the American Urological Association.

The impact of nocturia on quality of life often goes overlooked in clinical practice and clinical research, said press briefing moderator Tomas Griebling, MD, of the University of Kansas Medical Center in Kansas City.

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