José Cipolla-Neto, MD, PhD, Institute of Biomedical Sciences, University of Sa?o Paulo, and Fernanda Gaspar do Amaral, PhD, a professor at the Federal University of São Paulo, Brazil, have conducted an in-depth review of the literature on melatonin and its uses, reports Medscape.

Melatonin has been shown to affect a number of physiological processes, including downstream effects on the cardiovascular, reproductive, immune, respiratory, and endocrine systems, alongside energy metabolism.

“Melatonin synchronizes our organism’s temporal order both daily and on the seasonal time scale,” Cipolla-Neto commented in a press release from the São Paulo Research Foundation (FAPESP).

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