A CDC study found that melatonin overdoses increased during the COVID-19 pandemic. Two babies died and five children required mechanical ventilation after overdosing on melatonin supplements, according to the 10-year study.

A new study published by the CDC found that melatonin overdoses in children increased 530% from 2012 to 2021, with the largest spike — a 38% increase — occurring from 2019 to 2020, when the COVID pandemic started. The researchers looked at melatonin overdoses in children and teens.

More than 260,000 cases were reported to US poison control centers over the last decade, including more than 4,000 hospitalizations and nearly 300 that resulted in intensive care. Five children required mechanical ventilation and two children — a 3-month-old and a 1-year-old — died at home following melatonin poisoning.

The researchers said child-resistant packaging for melatonin “should be considered” and that healthcare providers need to better warn parents about the supplement’s “potential toxic consequences.”

The study’s lead researcher Dr. Karima Lelak, who is a pediatric emergency medicine physician at the Children’s Hospital of Michigan in Detroit, said melatonin may not be as harmless as people make it out to be, and that safe storage is absolutely critical. “Parents should really see melatonin just as any other medication that has the potential to do harm to kids, and it can be even more dangerous because it can look like candy,” Lelak told BuzzFeed News. “If a parent takes their melatonin after reading this paper and puts it in their medicine cabinet, I am humbled because I think that’s really a big take-home point: safe storage.”

Get the full story at buzzfeednews.com.