Obstructive sleep apnea (OSA) may be linked to low bone mineral density in adults, which could have implications for orthodontic treatment, according to a study led by University at Buffalo researchers.
The findings are crucial for individuals with sleep apnea, as low bone mineral density is an indicator of osteoporosis. In addition to increasing the risk of fractures, low bone mineral density also impacts oral health, causing teeth to become loose and dental implants to fail, according to senior author Thikriat Al-Jewair, DDS, associate professor of orthodontics in the UB School of Dental Medicine and director of the school’s Advanced Education Program in Orthodontics.
The researchers used cone beam computed tomography (CBCT), a type of X-ray, to measure bone density in the head and neck of 38 adult participants, half of whom had OSA. When controlling for age, sex, and weight, the participants with OSA had significantly lower bone mineral density than the participants without the condition.
Sleep apnea can cause hypoxia, inflammation, oxidative stress, and shortened breathing patterns. Each of these symptoms may have a chronic negative effect on bone metabolism and, ultimately, bone density, according to Al-Jewair.
“While the link between obstructive sleep apnea and low bone mineral density has yet to be fully explored, this study offers new evidence on their connection that could have several implications for orthodontic treatment,” says Al-Jewair, also assistant dean for equity, diversity, and inclusion in the UB School of Dental Medicine, in a press release. “If a patient has been diagnosed with sleep apnea, this can influence treatment planning and management. CBCT imaging has become an integral part of daily orthodontic practice and could be used as a screening tool for low bone mineral density. Orthodontists could then inform their patients of their propensity for low bone mineral density and encourage them to seek further consultation with their physician, as well as warn the patient of possible adverse outcomes, increased risks, and effects on treatment time.”
Future research with larger sample sizes is needed, says Al-Jewair in the release.