According to Ambra Stefani, MD, minor sleep-related movement disorders tend to be missed (more than misdiagnosed), as they are seldom and not easy to identify in video polysomnography, reports Neurology Advisor.

“SRBD may also be a cause of sleep disturbance and PLMS may be present, but a PLMD cannot be diagnosed if the PLMS is not the cause of the sleep disturbance,” Dr Stefani added. “Currently, treatment of PLMS is indicated only if a PLMD is diagnosed, and studies evaluating PLMD treatment are scarce. Dopaminergic treatment may even induce RLS in these patients. Few studies indicate possible efficacy of clonazepam and valproate on sleep quality, or of melatonin on PLMS index.”