CPAP seemed to be a more effective treatment than mandibular advancement devices and had an increasingly larger effect in more severe or sleepier OSA patients, reports a study published in The Lancet.

Excessive daytime sleepiness is the most important symptom of obstructive sleep apnoea and can affect work productivity, quality of life, and the risk of road traffic accidents. We aimed to quantify the effects of the two main treatments for obstructive sleep apnoea (continuous positive airway pressure and mandibular advancement devices) on daytime sleepiness and to establish predictors of response to continuous positive airway pressure.