Sleep Review‘s webinar Preventing and Managing Augmentation in Restless Legs Syndrome is now available for free and immediate on-demand viewing.

Restless legs syndrome (RLS) augmentation describes a not-uncommon phenomenon in which—after weeks, months, or years of a patient’s RLS being well controlled by a dopamine drug—symptoms become more intense, take less time to occur when at rest, manifest earlier in the day, return more quickly after taking therapeutic medication, and may spread to other parts of the body.

Science does not fully understand why augmentation occurs. Drug tolerance may be a component, but the phenomenon goes further than that.

In this free 1 hour and 6 minute webinar hosted and moderated by Sleep Review, attendees will learn:

  • how to differentiate augmentation from a simple medical worsening of the disorder over time
  • strategies to prevent augmentation
  • how to manage augmentation when it occurs

The on-demand version includes a recording of the live Q&A segment.



William G. Ondo, MD

William G. Ondo, MD
Houston Methodist Neurological Institute, Houston, Texas
William G. Ondo, MD, director of the Movement Disorders Clinic at the Houston Methodist Neurological Institute, has been diagnosing, treating, and researching RLS for more than 20 years. Ondo earned his medical degree from the Medical College of Virginia, then completed an internship at the University of North Carolina Hospital, a neurology residency at Duke University, and a movement disorders fellowship at the Baylor College of Medicine. He is board certified in adult neurology and sleep medicine.

Daniel Lee, MD, FAAN, FAASM

Daniel Lee, MD, FAAN, FAASM

Daniel Lee, MD, FAAN, FAASM
Baptist Health Neurology, Richmond, Ky
Daniel Lee, MD, is the medical director of the Sleep Research Center at Baptist Health System in Kentucky. He is board certified by the American Academy of Neurology and Psychiatry and the American Board of Sleep Medicine. His major research interests are circadian rhythm physiology, genetic engineered dopamine-3 gene knock-out, and pharmacologic therapy of RLS. Lee has published extensively in peer-reviewed medical journals and served on the National Scientific Advisory Board of Willis-Ekbom Disease Research. He is commissioned as Kentucky Colonel by Kentucky Governor for distinguished service and accomplishments, the highest honor awarded by the Commonwealth of Kentucky.

Mark Buchfuhrer, MD

Mark Buchfuhrer, MD

Mark Buchfuhrer, MD
Private Practice, Downey, Calif; Restless Legs Syndrome Clinic at the Stanford Center for Sleep Sciences and Medicine
Mark Buchfuhrer, MD, is a pulmonologist, sleep specialist, and expert in restless legs syndrome. He sees restless legs syndrome patients at his private practice in Southern California. He also practices at the monthly Restless Legs Syndrome Clinic at the Stanford Center for Sleep Sciences and Medicine, which has been certified as a Quality Care Center by the Restless Legs Syndrome Foundation. He is the medical advisor of a Southern California RLS support group. Buchfuhrer has authored and coauthored several books and medical articles on RLS including a 2016 consensus publication presenting guidelines for the prevention and treatment of augmentation.


This webinar is sponsored by

Arbor Pharmaceuticals

Arbor Pharmaceuticals is an Atlanta, Georgia-based specialty pharmaceutical company that provides prescription products for the cardiovascular, hospital, neuroscience, and pediatric markets.

Arbor is proud to be a corporate sponsor of nonprofit organizations that provide disease state information. Arbor believes in being a good corporate citizen by doing its part to help associations that focus on funding discovery of new medicines or helping people afflicted by diseases.

To learn more, visit

The webinar originally aired March 23, 2018.

Register to watch Preventing and Managing Augmentation in Restless Legs Syndrome (it’s free!). *If you already registered to watch the event, simply enter and submit your e-mail address in the text box indicated. No need to re-register.