Research presented at SLEEP 2017 found a correlation between sleep-disordered breathing and depression in adolescents, reports Medscape.
Participants were 20 outpatient adolescents with TRD (no response to two 6-week trials of antidepressants) and 20 healthy controls matched for sex and age. The severity of depressive symptoms was rated on the Beck Depression Inventory (BDI-II).
They found that rates of SDB (respiratory disturbance index > 10) were significantly higher in the TRD group than the control group (50% vs 15%; P = .018). In the TRD group, respiratory disturbances correlated with depressive symptoms (controlling for body mass index, r = 0.59; P = .007).
Interventional studies are required to determine whether SDB treatment could improve clinical outcomes early in mood disorders, Dr Chase said.
Get the whole story at www.medscape.com