Research presented at SLEEP 2017 found a correlation between sleep-disordered breathing and depression in adolescents, reports Medscape. 

Participants were 20 outpatient adolescents with TRD (no response to two 6-week trials of antidepressants) and 20 healthy controls matched for sex and age.  The severity of depressive symptoms was rated on the Beck Depression Inventory (BDI-II).

They found that rates of SDB (respiratory disturbance index > 10) were significantly higher in the TRD group than the control group (50% vs 15%; P = .018). In the TRD group, respiratory disturbances correlated with depressive symptoms (controlling for body mass index, r = 0.59; P = .007).

Interventional studies are required to determine whether SDB treatment could improve clinical outcomes early in mood disorders, Dr Chase said.

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